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Botanical guide

Ashwagandha

Some ashwagandha extracts may help with stress and sleep, but products are not interchangeable. KSM-66 uses root only; Sensoril uses root and leaf. Compare the extract, daily amount and safety considerations before choosing a product.

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In this guideIngredient basics, choosing & product comparison

What is ashwagandha?

Ashwagandha (Withania somnifera) is a plant used traditionally in South Asia. Supplements usually contain root powder, root extract or root-and-leaf extract. Concentrated extracts can be standardised for naturally occurring compounds called withanolides, a group of steroidal lactones.

What might ashwagandha help with?

Some short-term studies suggest that particular ashwagandha extracts may help with perceived stress and sleep. Findings depend on the extract and study population; the name “ashwagandha” alone does not identify a clinically equivalent product.

Exercise-related outcomes have also been investigated, but evidence is not sufficient to promise broad benefits for every preparation. It is more useful to match an extract to relevant human research than to choose the largest milligram number.

What does the research say about stress, cortisol and sleep?

Human research

Small trials suggest benefits, rather than a universal effect

NIH's Office of Dietary Supplements describes several short trials reporting improvements in stress or sleep measures. Studies use different root or root-and-leaf extracts, doses and participants; many are small. NCCIH considers evidence for anxiety less clear.

For example, a 2012 placebo-controlled trial enrolled 64 adults with chronic stress and tested 300 mg of a concentrated root extract twice daily for 60 days. Stress scores and serum cortisol fell more in the extract group. This is a study regimen, not a personal dose recommendation.

Does lower cortisol mean better health?

Not necessarily. Cortisol is a normal hormone, and a study finding does not show that everyone should try to lower it. The trial does not establish treatment for a hormonal disorder, nor prove that a different extract will produce the same result.

Is ashwagandha safe to take every day?

Short-term tolerability is better studied than long-term safety. NIH sources describe use for up to about three months, but this is not a guaranteed safe period for every person or preparation. Continuous use over many months or years remains insufficiently understood.

Do you need to cycle it or take breaks?

There is no established evidence-based cycling schedule that makes long-term use safe. A planned week off does not resolve uncertainty about the extract, dose or individual risk. Reassess whether it is helping rather than treating it as an indefinite daily essential.

Side effects and who should avoid it

Possible effects include stomach upset, diarrhoea and drowsiness. Rare liver injury has been reported. Avoid during pregnancy and breastfeeding. Thyroid or autoimmune disease, upcoming surgery and hormone-sensitive prostate cancer require particular caution; seek professional advice rather than self-selecting a product.

Interactions may involve thyroid hormones, sedatives, anticonvulsants, immunosuppressants, and diabetes or blood-pressure medicines. Stop use and seek medical advice for yellow skin or eyes, dark urine or marked unexplained nausea or fatigue, especially if you have liver disease.

What exactly is in the capsule?

Common ashwagandha formats

Root powderLess concentrated material; a larger milligram number is not directly comparable with a standardised extract.
Root extractConcentrated extract, sometimes standardised to a stated percentage of withanolides.
Root + leaf extractUsed by some branded extracts such as Sensoril® and Shoden®.
Branded extractKSM-66®, Sensoril® and Shoden® use different plant material and standardisation approaches.

KSM-66 vs Sensoril: what is the difference?

KSM-66 is a root-only extract; Sensoril combines root and leaf. They also differ in standardisation and the amounts used in studies. Neither name alone makes a finished supplement the better choice.

FeatureKSM-66®Sensoril®
Plant materialRoot onlyRoot and leaf
Typical label standardisationAround 5% withanolidesOften at least 10% withanolide glycosides; check the exact label
Research contextRoot-extract trials include stress and sleep outcomesRoot-and-leaf trials include stress and sleep outcomes
How to compareMatch the named extract, daily serving and relevant trial. Percentages alone do not establish dose equivalence.

Is 10% twice as strong as 5%?

It is not a reliable clinical comparison. Labels can refer to different groups of compounds and analytical methods. Even when a percentage helps calculate a declared constituent amount, it does not establish twice the benefit, or that a smaller capsule can replace a larger one.

What about Shoden?

Shoden® is another concentrated root-and-leaf extract with its own standardisation and research. Keep it separate when comparing formulations; do not convert between branded extracts using milligrams alone.

For a root-only preference, identify products that actually name the root extract. For a Sensoril product, confirm the branded ingredient and daily serving. Check added actives too: black pepper, L-theanine or other ingredients make the whole formula different.

Compare ashwagandha extracts and daily amounts →

What should you compare?

Plant part

Root only or root + leaf.

Extract / brand

KSM-66®, Sensoril®, Shoden® or a non-branded standardised extract.

Withanolide standardisation

A useful concentration clue when stated, but not an effectiveness score.

Daily serving

Compare the manufacturer's full recommended daily amount, not one capsule in isolation.

Other ingredients

Some products include black pepper extract, L-theanine, magnesium or other compounds.

Vegan status & format

Capsules and softgels differ in shell ingredients and convenience.

Health information: This guide provides general information, not personal medical advice. Botanical supplements can have contraindications and interactions; check the product warnings and seek appropriate professional advice where relevant.

Product comparison

Compare ashwagandha supplements

Compare daily amount, amount per unit, serving, extract, plant part, standardisation, format, other active ingredients and vegan suitability.

Do not rank by the biggest milligram number. Ashwagandha products may use root powder, root extract or root-and-leaf extracts with very different concentrations. Named extracts also have different research histories.

Default order: labelled minimum daily ashwagandha amount, lowest to highest; equal amounts alphabetically. This is not an effectiveness ranking.

ProductDaily amountAmount / unitRecommended daily servingExtractPlant partStandardisationFormatOther active ingredientsVegan
Swanson Sensoril® AshwagandhaView product ↗125 mg125 mg1 capsule dailySensoril®Root + leafMin. 0.4% withanolide glycosidesCapsule—Not confirmed
Life Extension Optimized AshwagandhaView product ↗250 mg125 mg1 capsule twice daily on an empty stomachSensoril®Root + leaf extract32% oligosaccharides; 10% withanolide glycoside conjugatesVegetarian capsule—Vegetarian; vegan not confirmed
Sports Research AshwagandhaView product ↗500–1,000 mg250 mg2 softgels 1–2× daily with foodShoden® + ashwagandha powderRoot + leaf120 mg Shoden® in 2-softgel serving; Shoden standardised extractVegan softgelBioPerine® black pepper extract, coconut MCTYes
NOW Foods KSM-66 Ashwagandha®View product ↗600 mg600 mg1 capsule dailyKSM-66®RootKSM-66® full-spectrum root extractVeg capsule—Yes
NutraBio KSM-66® AshwagandhaView product ↗600 mg600 mg1 capsule dailyKSM-66®RootStandardised to 5% withanolidesCapsule—Vegetarian
NOW Foods Ashwagandha Standardized ExtractView product ↗900–1,350 mg450 mg1 capsule 2–3× dailyStandardised extractRoot + leafMin. 2.4% total withanolidesVeg capsule—Yes
EU health claim details
×

Authorised health claims

0 authorised

No EU-authorised health claim is listed for this ingredient.

On-hold botanical claims

Pending EU-level consideration — not final authorised claims
10 on hold
●  Stress, relaxation and mental well-being.Ashwagandha · Submitted botanical claim theme
Claim status
On hold / pending EU-level consideration

Ingredient
Withania somnifera (Ashwagandha)

Claim ID
2183

EFSA question
EFSA-Q-2008-2916

Regulatory note
This is not a final EU-authorised health claim.
●  Cardiovascular health.Ashwagandha · Submitted botanical claim theme
Submitted example wording
Beneficially affects the heart and cardiovascular system.

Ingredient
Withania somnifera (Ashwagandha)

Claim ID
2503

EFSA question
EFSA-Q-2008-3236

Status
On hold — not a final EU-authorised health claim.
●  Adaptogenic properties.Ashwagandha root · Submitted botanical claim theme
Submitted example wording
Ashwagandha has adaptogenic properties.

Ingredient
Ashwagandha root (Withania somnifera)

Claim ID
3251

EFSA question
EFSA-Q-2008-3983

Status
On hold — not a final EU-authorised health claim.
●  Physical and mental capacities.Ashwagandha · Submitted botanical claim theme
Submitted example wording
Helps to maintain physical and mental capacities in cases of weakness, exhaustion, tiredness and loss of concentration; nerve tonic.

Ingredient
Withania somnifera

Claim ID
3657

EFSA question
EFSA-Q-2008-4380

Status
On hold — not a final EU-authorised health claim.
●  Mental balance, stress and sleep.Ashwagandha root · Submitted botanical claim theme
Submitted claim scope
Resistance to stress, mental balance, mental function, onset of sleep, learning, memory, recall and emotional stability.

Ingredient
Withania somnifera root

Claim ID
4194

EFSA question
EFSA-Q-2008-4905

Status
On hold — not a final EU-authorised health claim.
●  Energy and vitality.Ashwagandha · Submitted botanical claim theme
Claim status
On hold / pending EU-level consideration

Ingredient
Withania somnifera (Ashwagandha)

Claim ID
4195

EFSA question
EFSA-Q-2008-4906

Regulatory note
This is not a final EU-authorised health claim.
●  Respiratory health.Ashwagandha root · Submitted botanical claim theme
Submitted example wording
Helps maintain the health of the respiratory system.

Ingredient
Withania somnifera root

Claim ID
4196

EFSA question
EFSA-Q-2008-4907

Status
On hold — not a final EU-authorised health claim.
●  Rejuvenation.Ashwagandha root · Submitted botanical claim theme
Submitted example wording
Has a general rejuvenating effect.

Ingredient
Withania somnifera root

Claim ID
4197

EFSA question
EFSA-Q-2008-4908

Status
On hold — not a final EU-authorised health claim.
●  Reproductive health.Ashwagandha root · Submitted botanical claim theme
Submitted claim scope
Female reproductive organs, strength in pregnancy, male sexual function, sperm mobility and sperm count.

Ingredient
Withania somnifera root

Claim ID
4198

EFSA question
EFSA-Q-2008-4909

Status
On hold — not a final EU-authorised health claim.
●  Skin health.Ashwagandha root · Submitted botanical claim theme
Submitted example wording
Helps maintain the health of the skin.

Ingredient
Withania somnifera root

Claim ID
4199

EFSA question
EFSA-Q-2008-4910

Status
On hold — not a final EU-authorised health claim.
What this means: Withania somnifera appears among botanical Article 13 claims that remain on hold. Those claims have not received final EU authorisation.

Sources & regulatory details

Sources & further reading